内容简介:  

郭宏记1，刘少英2
(1.浙江大学 物理系，浙江 杭州 310027；2.浙江大学 心理系，浙江 杭州 310027)
摘要：持变概率法,是一种统计一维序列持续变化概率的方法，可用于统计核酸序列碱基交替变化情况，通过此方法得出：1）核酸序列中的持变概率与持变次数呈指数关系变化；2）人类各染色体的持变指数有一定的稳定性，受个体、测序方向的影响较小；3）持变指数具有特征性，核酸序列中产生的持变指数与随机序列中产生的持变指数有着明显差异。由此推断生物界可能存在着某种内编码规则约束着核酸进行编码，这一规则的外在表征即为持变指数。
关键词：核酸序列；持变概率；持变指数
中图分类号：Q61, Q343.1, O414.2 文献标志码：A
Using Persistent Changing Probability for Analysis of Nucleotide Sequences
GUO Hong-ji1, LIU Shao-ying2
(1.Department of physics, Zhejiang University, Hangzhou 310027, China; 2.Depart of psychology , Zhejiang University, Hangzhou 310027, China)
Abstract: A new method named Persistent Changing Probability is presented and applied to quantify the changing of DNA nucleotide sequences. Using this method we can get those results: 1) Exponential distribution is found between Persistent Changing Probability and Persistent Changing Number. 2) Human being’s Persistent Changing Exponents are stable, which will not influenced too much by individual or the orientation of sequence measurement. 3) This Persistent Changing Exponent is obviously different from which we can get from random series. This indicated that there must be some intrinsic rules to control the coding of nucleotide sequences, which can be represented by Persistent Changing Probability.
Key Words: Nucleotide Sequences; Persistent Changing Probability; Persistent Changing Exponent.

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